The Relationship Between Retinal Vein Occlusions and ABO (H) Blood Groups
Mustafa GÖK1, Aslıhan UZUN2, Hasan Burhanettin KAPTI1, Özgür KARA3
1M.D. Asistant Professor, Ordu Universitu Training and Research Hospital, Eye Clinic, Ordu/TURKEY 2M.D, Ordu Universitu Training and Research Hospital, Eye Clinic, Ordu/TURKEY 3M.D. Fatsa State Hospital, Eye Clinic, Ordu/TURKEY
Purpose: To evaluate the relationship between ABO (H) blood groups and retinal vein occlusions.
Materials and Methods: Medical records of 54 patients diagnosed with retinal vein occlusion (RVO) and 47 age and sex matched individuals
as control group were reviewed retrospectively. ABO(H) blood groups, Rh factors, the history of diabetes mellitus, hypertension, smoking,
deep venous thrombosis, or cerebrovascular occlusion were recorded. All patients were divided into two subgroups; patients with central retinal
vein occlusion (CRVO, n=22) and patients with branch retinal vein occlusion (BRVO, n=32). The frequencies of ABO (H) blood groups, Rh
factors and other parameters in RVO group, CRVO and BRVO subgroups were analyzed statistically.
Results: The frequency of non-O blood groups was statistically higher in RVO group than control group (p≤0.017, OR: 0.37 CI: 0.16-0.84).
Although the frequency of A and B blood groups were statistically higher in RVO group, there was no significant difference in AB blood group
between RVO and control group. The frequency of non-O blood groups was insignificantly higher in BRVO subgroup whereas non-O blood
groups were significantly higher in CRVO subgroup (p≤0.015). The distribution of Rh groups was not statistically different in all groups.
Moreover there was no statistically significant difference in ABO(H) (p≤0.160, OR: 2.71 CI: 0.65-11.24) and Rh groups between CRVO and
Conclusion: Having a non-O blood group can be associated with an increased risk of RVO.
Retinal vein occlusion, ABO blood-group system