Retina-Vitreous
2010 , Vol 18 , Num 1
Fundus Autofluorescence in Cystoid Macular Edema: Can it Be an Ancillary Test?
1Yeditepe Üniversitesi Tıp Fakültesi Hastanesi, Göz Has. A.D., İstanbul, Yrd. Doç. Dr.2Yeditepe Üniversitesi Tıp Fakültesi Hastanesi, Göz Has. A.D., İstanbul, Doç. Dr.
3Yeditepe Üniversitesi Tıp Fakültesi Hastanesi, Göz Has. A.D., İstanbul, Prof. Dr. Purpose: To evaluate the findings of fundus autofluorescence (FAF) in cystoid macular edema (CME).
Materials and Methods: Sixty-seven eyes of 55 patients having CME secondary to diabetic retinopathy, retinal vein occlusion, uveitis, cataract extraction, epiretinal membrane and age-related macular degeneration were recruited. All cases were evaluated by FAF, fundus fluorescein angiography (FFA) and optical coherence tomography (OCT).
Results: Mean central macular thickness was detected as 419.3±131.1μm by OCT. FAF images revealed increased autofluorescence signal in a round or oval fashion at the fovea corresponding to the flower petaloid pattern on FFA. Dark septa within the petaloid leakage on FFA were seen as decreased autofluorescent areas on FAF imaging. Sixtyfour eyes had CME on both FFA and FAF. In one eye of a patient having macular edema after cataract extraction, FAF revealed no CME when CME was observed on FFA. In 2 eyes, although there was no typical leakage pattern on FFA, CME was apperant on FAF imaging.
Conclusions: In addition to FFA and OCT findings, FAF data may reveal noteworthy information in CME. FAF imaging may be used as a non-invasive and rapid ancillary test for the diagnosis of eyes having CME. Keywords : Cystoid macular edema, fundus autofluorescence