2M.D. Asistant Professor, Recep Tayyip Erdogan University Facuty of Medicine, Department of Physical Medicine and Rehabilitation, Rize/TURKEY Purpose: To investigate pre- and post-treatment macular and peripapillary nerve fiber layer (RNFL) changes in eyes with acute anterior uveitis (AU) by optical coherence tomography (OCT).
Materials and Methods: Seventeen eyes of 17 patients with AU (uveitic eyes) and unaffected fellow (control) eyes of these patients were enrolled to the study. Peripapillary RNFL, optic nerve head, and macular scans were performed using Cirrus HD OCT. OCT measurements were performed at baseline (before starting treatment) and two months after the remission for each subject.
Results: The mean age of the patients was 32.0±12.3 years. Uveitic eyes had significantly higher central subfield thickness (CST) values than healthy fellow control eyes (p=0.010). CST decreased significantly after the treatment compared with baseline (p=0.001) in the uveitic eyes, whereas there was no significant difference between pre- and post-treatment CST values of healthy fellow control eyes.
Conclusions: We have shown that eyes with AU had higher CST than healthy fellow eyes in Cirrus HD OCT. OCT devices may be useful for noninvasive evaluation of microscopic macular changes that are not yet obvious in a standard clinical examination.
Keywords : Anterior uveitis, macular thickening, optical coherence tomography