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D. Associate Professor, Ankaar Training and Research Hospital, Eye Clinic, Ankara/TURKEY Anti-vascular endothelial growth factor was revolutionized the treatment of wet age related macular degeneration. This paper will review currently available anti-VEGF agents and evidencebased treatment strategies. Keywords : Age related macular degeneration, choriodal neovascular membrane, vascular endothelial growth factor, ranibizumab, bevacizumab, aflibercept