Retina-Vitreous
2015 , Vol 23 , Num 4
Evaluation the Effects of Anti-VEGF Agents on Retina in Age-Related Macular Degeneration
1M.D. Mus State Hospital, Eye Clinic, Mus/TURKEY2M.D. Professor, Necmettin Erbakan University Faculty of Medicine, Department of Ophthalmology, Konya/TURKEY
3M.D. Associate Professor, Necmettin Erbakan University Faculty of Medicine, Department of Ophthalmology, Konya/TURKEY
4M.D. Asistant Professor, Necmettin Erbakan University Faculty of Medicine, Department of Ophthalmology, Konya/TURKEY
5M.D., Necmettin Erbakan University Faculty of Medicine, Department of Medical Education and Informatics, Konya/TURKEY Purpose: Evaluation the effects of intravitreal anti-VEGF agents on retina using spectral optical coherence tomography (OCT) in age related macular degeneration.
Materials and Methods: Retinal nerve fiber layer (RNFL) and macular thickness measurements were made and compared before and after 6 intravitreal anti-VEGF injections in 78 eyes with exudative age-related macular degeneration (ARMD).
Results: After the anti-VEGF injections, RNFL thickness dropped to 101.17±1.49 μ from 103.24±2.06 μ (p=0.362). Macular thickness regressed to 358.59±13.52 μ from 420.15±16.79 μ (p<0.001).
Conclusion: While anti-VEGF agents cause a significant decrease in macular thickness, they cause no significant decrease in RNFL thickness.
Keywords : Anti-VEGF, age-related macular degeneration, macular edema