2M.D. Asistant, Erciyes University Faculty of Medicine Department of Ophthalmology, Kayseri/TURKEY Purpose: To evaluate the effects of photodynamic therapy (PDT) in chronic central serous chorioretinopathy (CCSC) by measuring visual acuity, central foveal thickness, central choroidal thickness.
Material and Methods: 29 eyes of 21 patients with chronic CCSC who received PDT and were followed-up for at least 6 months after PDT were included in this study. Visual acuity, central foveal thickness ,central choroidal thickness were assessed before PDT and within the first week ,first month,third and sixth month after PDT.
Results: The mean visual acuity by using Snellen chart was 0.71 at baseline, 0.62 within the first week after PDT, 0.76 at first month, 0.85 at third month and 0.88 at sixth month. The mean central foveal thickness was 364.52±58.69 μm before treatment and 352.12±62.36 μm within the first week. It decreased significantly to 202.66±27.07 μm at first month after PDT. The mean central choroidal thickness was 435.88±59.15 μm before treatment and it increased significantly to 491.52±38.21 μm within the first week. During the follow-up period, it decreased significantly to 329.44±38.36 μm at 1st month after PDT. There was no significant difference between the first month and the third and sixth month thickness measurements. Complete resolution of subretinal fluid at the macula was achieved in 25 eyes at the 1st month, in 28 eyes at the third month and subsequent follow-up visits.
Conclusions: PDT is an effective and safe method in the treatment of chronic CCSC with anatomical and functional success. After treatment, the therapy resulted with significant increase in visual acuity and decrease in central foveal and choroidal thicknesses in a short time.
Keywords : Photodynamic therapy, choroidal thickness, central serous chorioretinopathy