Turkish Abstract Abstract Article PDF Similar Articles

OMÜ Tıp Fak. Göz Hst. ABD., OMÜ Tıp Fak. Pediatri ABD By means of modern chemotherapy methods in ALL, isolated ocular relapse occurs rarely during maintenance therapy. Relapses occur in humour aqueous where chemotherapeutics are unsuccessful to penetrate in and come out with leukocyte accumulation in anterior chamber. No relapse is reported in a child patient with bilateral exudative retinal detachment, during maintenance therapy.
Case: A 3.5 years old child patient with ALL came out with visual lost and strabismus in fifteenth month of maintenance therapy. He had bilateral exudative retinal detachment. The diagnose was confirmed with B-scan ultrasonography, orbital MR and CT. There was no blast in humour aqueous aspiration and there was no relapse in CNS and bone marrow. After two months, painful glaucoma developed in both eyes and consolidation therapy was carried out. No improvement occurred in detachment end the patient was died because of neutropenic sepsis at the end of the third month. There were 700 PNL in 1 mm ³ cerebospinal fluid in post-mortem LP. The family of the patient disapproved post-mortem pathological study.
This case shows that bilateral exudative retinal detachment can occur in childhood ALL. Keywords : ALL, Retinal Detachment, Maintenance therapy