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Yıldırım Beyazıt Üniversitesi Tıp Fakültesi, Göz Anabilim Dalı, Ankara - TÜRKİYE Diabetic Rethinopathy (DR) and Age-related Macular Degeneration (AMD) are common retinal diseases that can result with visual impairment. In spite of the new developments in the treatment modalities of these diseases there are stil many ongoing research in patophysiology and treatment. The choice of experimental animal model is very important in these researches. There are several models reported in the literature. However, an ideal model has not yet been reached. In this review, it is aimed to share information about experimental animal models that can be used for DR, AMD and similar retinal diseases. Keywords : Diabetic rethinopathy, age-related macular degeneration, experimental animal models