2Doç. Dr., Elazığ Eğitim ve Araştırma Hastanesi, Göz Hastalıkları Kliniği, Elazığ, Türkiye
3Yrd. Doç. Dr., Gaziosmanpaşa Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Tokat, Türkiye Purpose: To compare choroidal thickness (CT), retinal thickness (RT) and retinal nerve fiber layer thickness (RNFL) in eyes of unilateral Pseudoexfoliation (PEX) patients without glaucoma and compare them with healthy controls.
Material and Methods: Sixty eyes of 30 PEX patients without glaucoma and 32 eyes of 32 healthy subjects were included in this study. The CT, RT, RNFL measurements were compared between PEX, PEX unaffected eye and control groups. All optical coherence tomography (OCT) scans and measurements were acquired by Spectralis OCT. CTs were measured with enhanced depth imaging (EDI) mode of Spectralis OCT. The RTs was measured using automatic segmentation values of the Spectralis OCT. Optic disc protocol was used to measure RNFLs.
Results: Compared with controls nasal RT was thinner in PEX (p=0,009) and PEX unaffected eye (p=0,013) groups. Nasal retina in PEX and PEX unaffected eye was similar (p=0,992). Temporal RT was also thinner in PEX (p=0,004) and PEX unaffected eye (p=0,009) than control group. Temporal RT was similar in PEX and PEX unaffected eyes (p=0,975).Global RNFL was thinner in PEX group (p=0,011) than control group. Global RNFL was similar in PEX and PEX unaffected eye groups (p=0,433). Nasal inferior RNFL in PEX group was thinner than control group (p=0,026). Nasal inferior RNFL was similar in PEX and PEX unaffected eye groups (p=0,358).
Conclusion: RT and RNFL may be thinner in eyes with PEX patients without glaucoma and in fellow eyes of PEX patients than age-matched controls.
Keywords : Choroidal thickness, Optical coherence tomography, Pseudoexfoliation, Retinal nerve fi ber layer thickness, Retinal thickness