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Retina Arter Tıkanıklıkları ve Tedavisi...
Santral Retinal Ven Tıkanıklığı Güncel Tedavisi...
Central Retinal Artery Occlusion As the Cause of Unilateral Concentric Narrowing of Visual Field and Presence of Cilioretinal Artery...
Bilateral Optic Disc Drusen
Vascular Endothelial Growth Factor and Anti VEGF Agents...
Central Retinal Artery Occlusion As the Cause of Unilateral Concentric Narrowing of Visual Field and Presence of Cilioretinal Artery...
Retina Arter Tıkanıklıkları ve Tedavisi...
Morning Glory Syndrome Associated with Retinochoroidal Coloboma...
Santral Retinal Ven Tıkanıklığı Güncel Tedavisi...
Bilateral Optic Disc Drusen
PureSee Kesintisiz Yüksek Kalitede Görüş
Retina-Vitreous 2020 , Vol 29 , Num 3
Turkish Abstract Abstract Free Full Text English Similar Articles Mail to Author
Efficacy of Intravitreal Bevacizumab Monotherapy in the Treatment of Retinopathy of Prematurity
Caner KARA1, Ikbal Seza PETRICLI1, Aysegul ARMAN1, Cagatay OZCAN2, Fatma IYIGUN2
1MD., Etlik Zübeyde Hanim Women?s Health Education and Research Hospital, Department of Ophthalmology, Ankara, Turkey
2MD., Etlik Zübeyde Hanim Women?s Health Education and Research Hospital, Department of Neonatology, Ankara, Turkey
DOI : 10.37845/ret.vit.2020.29.36 Purpose: To evaluate the results of intravitreal bevacizumab (IVB) monotherapy applied for retinopathy of prematurity (ROP) during a 6 year period in a tertiary referral for ROP.

Materials and Methods: The fi les of patients treated with IVB for ROP between January 2012 and October 2018 were evaluated retrospectively. Gestational age, birth weight, indications and results of IVB monotherapy and complications were recorded.

Results: One hundred twenty three eyes of 69 patients were included in the study. Seventy-six eyes (58.5%) of 40 patients had aggressive posterior retinopathy of prematurity (AP-ROP) and 47 eyes (41.3%) of 29 patients had classic Type 1 ROP. One hundred nine eyes (88.7%) of 62 patients were responsive to initial IVB injection but 14 eyes (11.3) of seven patients were non-responsive. Complete resolution was detected in 76 eyes (69.7%) of 44 patients responsive to initial IVB treatment, whereas in 29 eyes (26.6%) of 16 patients, ROP recurred within a mean period of 8.0 ± 3.0 weeks. In four eyes (3.6%) of two patients, peripheral vascularization was not completed.

Conclusion: Although a signifi cant number of patients were responsive to IVB injection, recurrence was an important disadvantage. Thus, long term and close follow up examinations are crucial after IVB injection. Keywords : Bevacizumab, retinopathy of prematurity, recurrence, laser coagulation, VEGF

PureSee Kesintisiz Yüksek Kalitede Görüş
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