Material-Methods: The study included 30 patients diagnosed with central serous chorioretinopathy (CSCR) with optic coherence tomography (OCT) and fundus fluorescein angiography (FFA) (group 1) and an age and gender-matched healthy control group (group 2). The vitamin D levels of both groups were examined.

Results: There was no signifi cant difference between the groups in respect of age or gender (p>0.05, p>0.05, respectively). Vitamin D levels were determined as 20.16 ±7.03 ng/ml in group 1 and 28.56±6.59 ng/ml in group 2. The mean vitamin D level of group 1 was determined to be statistically signifi cantly lower than that of group 2 (p<0.05).

Conclusions: The low vitamin D levels determined in the cases with central serous chorioretinopathy could play a role in the pathophysiology of the disease. There is a need for further studies to determine the effect of vitamin D on the disease process and the changes that could occur with vitamin replacement therapy. Keywords : Vitamin D, Central serous chorioretinopathy, Pathophysiology