Retina-Vitreous
2003 , Vol 11 , Num 0
PRIMARY INTRAOCULAR LYMPHOMA DIAGNOSED BY CHORIORETINAL BIOPSY
1GATA Göz Hastalıkları AD., Ankara2GATA Patoloji AD., Ankara Purpose: To point out the necessity of chorioretinal biopsy for diagnosing primary intraocular lymphoma and to discuss the diagnose and treatment.
Findings: Presented here is a patient with the complaint of blurred vision and floaters in her right eye. At the time of presentation, moderately vitreous cells, edema at the inferior border of optic nerve head and creamy chorioretinal lesions were detected. Etiological evaluation was negative. Vitreous biopsy and diagnostic vitrectomy showed no evidence of malignancy. Then, Chorioretinal biopsy was applied and non-Hodgkin's lymphoma was diagnosed. B lymphocytes were positive for CD20. Radiotherapy and systemic chemotherapy were performed. 6 months later central nervous system involvement occurred and radiotherapy was applied to whole brain. The left eye was involved one year later and it was treated with intravitreal injections of methotrexate and remission was obtained.
Results: In patients presented with masquerading syndrome and with retinochoroidal lesions chorioretinal biopsy should be performed promptly after unresponsive vitreous biopsy or diagnostic vitrectomy. Keywords : Primary intraocular lymphoma, diagnose, treatment