Retina-Vitreous
2009 , Vol 17 , Num 1
Long-Term Follow-Up of a Case with Recurrent Acute Posterior Multifocal Placoid Pigmentous Epitheliopathy
1Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Göz Hast. A.D., Trabzon, Doç. Dr.2Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Göz Hast. A.D., Trabzon, Yrd. Doç. Dr.
3Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Göz Hast. A.D., Trabzon, Uzm. Dr. In this study, we present the clinical findings of a 26-year old male patient admitting to ophthalmology outpatient department with the complaint of decreased vision and was diagnosed as acute posterior multifocal placoid pigmentous epitheliopathy (APMPPE) after a detailed ophthalmological examination. At the time of first admission, visual acuity was 0.8 on the right and 1.0 on the left. His biomicroscopical anterior segment findings were within normal limits. In his fundoscopic examination, there were pigmentary changes of the retina on the right due to his previous episodes. Fundoscopic findings of the left eye were within normal limits. During the seven year follow-up period, in the region corresponding to the retinal pigment epithelium- choriocapillaris layer, focal grayish-white placoid type new lesions due to APMPPE episodes developed three times on the left eye and once on the right. The patient was given prednisolone at a dose of 1mg/kg during his attacks. Each episode resolved approximately within three weeks by leaving characteristic pigmentary changes in the retina. Fluorescein angiography examination performed during the inactive phase of the patient demonstrated staining pattern correlating with APMPPE. Abnormal retinal pigment epitelium-choriocapillaris junction was observed in optical coherence tomography. The patient did not develop a new episode during last 24-month follow-up, his visual acuity was preserved as 0.6 on the right and 1.0 on the left. As has been observed in this case, APMPPE can exhibit clinical features like unilateral frequent recurrences. Increases in the number of recurrences and involvement of fovea adversely affect the visual prognosis. Keywords : Acute posterior multifocal placoid pigment epitheliopathy, fluorescein angiography, low vision, optical coherence tomography