Retina-Vitreous
2009 , Vol 17 , Num 3
Regression of Choroidal Neovascularization Secondary to Pathologic Myopia after Intravitreal Injection of Bevacizumab
1Saint Luis Universitesi Oftalmoloji Departmanı, ABD, Prof. Dr.2Mersin Üniversitesi Tıp Fakültesi Hastanesi Göz Hastalıkları A.D., Mersin, Doç. Dr. We present a case of choroidal neovascular membrane (CNV) regression following a single intravitreal injection of bevacizumab in a patient with pathologic myopia.
Intravitreal bevacizumab (1.25 mg/0.05 cc) was injected in one eye of a 27 year-old patient with subfoveal CNV associated with pathologic myopia. Initial, 2-week and 8-week post-injection fluorescein angiography (FA) and Optical coherence tomography (OCT) were obtained. Single case reports are exempt from institutional review board approval at our institution.
FA confirmed regression of CNV. Best corrected visual acuity (BCVA) improved from 20/400 to 20/200 and remained stable. OCT data were markedly improved two weeks after injection and remained stable thereafter.
Intravitreal injection of bevacizumab may be an effective alternative treatment for CNV secondary to pathologic myopia. Keywords : Bevacizumab; pathologic myopia; intravitreal injection; choroidal neovascularization