Retina-Vitreous
2009 , Vol 17 , Num 4
Association Between Central Corneal Thickness and Age-Related Macular Degeneration
1Gazi Üniversitesi Tıp Fakültesi, Göz hastalıkları A.D., Ankara, Uzm. Dr.2Gazi Üniversitesi Tıp Fakültesi, Göz hastalıkları A.D., Ankara, Doç. Dr.
3Gazi Üniversitesi Tıp Fakültesi, Göz hastalıkları A.D., Ankara, Prof. Dr. Purpose: To determine any relationship between the development of age-related macular degeneration (AMD) and central corneal thickness (CCT).
Material and Methods: The CCT of patients with neovascular or nonneovascular AMD and of healthy control subjects were measured by using ultrasound corneal pachymetry. ANOVA test was used to compare the CCT between the groups.
Results: The mean age was 71.1 years in the AMD group, and 65.5 years in the control group. There were 100 eyes (100 patients,1 eye from each patient) in the AMD group and 116 eyes (116 patients,1 eye from each patient) in the control group. Half of the 100 eyes with AMD had neovascular AMD and the remaining had nonneovascular AMD. The mean CCT was 550.29±28.58 μ (462-620) in the AMD group as a total and 547.75±33.80 μ (485-650) in the control group (p>0.05). The CCT of neovascular AMD eyes was thinner (545.45±25,26 μ) (472-589) than that of both the control group (547.75±33.80 μ) and the nonneovascular AMD group (557.35±31.00 μ) (462-620), but the difference was not statistically significant. The difference between the neovascular and nonneovascular AMD groups was not statistically significant (545.45 vs. 557.35 μ, p=0.07).
Conclusion: CCT do not seem to have an association with the development of neovascular or nonneovascular AMD. Keywords : Corneal thickness, age related macular degeneration