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M.D. Asistant Professor, Çanakkale 18 Mart University Faculty of Medicine, Department of Ophthalmology, Çanakkale/TURKEY A 55 years old man presented to our clinic with a 3 month history of blurred vision and micropsia in his left eye. He was previously diagnosed with unilateral glaucoma and treatment was initiated with topical latanoprost 0.005% and brimonidine tartrate/timolol maleate 0.2%/0.5% combination for the left eye in another clinic. The symptoms occurred one month after the initiation of glaucoma treatment. Fundus examination, optical coherence tomography and fluorescein angiography revealed a juxtafoveal neurosensory detachment which was coherent with central serous chorioretinopathy (CSC). After the cessation of latanoprost treatment, his clinical status improved and almost complete resolution of neurosensory detachment was observed spontaneously. The use of topical latanoprost may lead to CSC. Clinicians should consider this complication especially in patients presented with decreased visual acuity while using latonoprost Keywords : Central serous chorioretinopathy, latanoprost, glaucoma