Retina-Vitreous
2022 , Vol 31 , Num 1
Retina and Apoptosis
Assoc. Prof. Dr., FEBO, Baskent University Hospital, Department of Ophthalmology, Ankara, Turkey
DOI :
10.37845/ret.vit.2022.31.15
It is known that apoptosis plays a role in the pathogenesis of many retinal diseases. Diabetic retinopathy, age-related macular degeneration, retinitis
pigmentosa, retinopathy of prematurity and retinoblastoma are examples of these diseases. Several ocular and extraocular neurodegenerative
diseases share common feature early and pathological death of retinal cells. This provides a potential early diagnosis window in which to delay
and possibly halt pathologic processes before they cause significant harm. Agents with mechanisms that reduce, or delay apoptosis are still
being investigated as treatment modalities in retinal diseases.
Keywords :
Apoptosis, Retinal endothelium, TUNEL technique