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Assoc. Prof., World Eye Hospital Eye Clinic, Retina Department, Konya, Türkiye DOI : 10.37845/ret.vit.2024.33.13 A 42-year-old male patient treated with pneumatic retinopexy for rhegmatogenous retinal detachment in his left eye on anticoagulant therapy with phakic anterior chamber intraocular lens (IOL) is presented. The methods currently used in the treatment of rhegmatogenous retinal detachments are scleral buckling, pars plana vitrectomy (PPV), and pneumatic retinopexy. However, the development of cataracts after PPV may be difficult to treat in a patient with an anterior chamber lens. Also, intraoperative and postoperative hemorrhagic complications after PPV and scleral buckling surgery may negatively affect the surgical results. Pneumatic retinopexy should be considered as the first treatment method for patients with anterior chamber IOL on systemic anticoagulation or antiplatelet agents to protect them from surgical difficulties of cataract surgery and hemorrhagic complications of PPV and scleral buckling. Keywords : Pneumatic retinopexy, Rhegmatogenous retinal detachment, Systemic anticoagulation, Anterior chamber intraocular lens