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¹M.D. Asistant, GATA Haydarpasa Training and Research Hospital, Eye Clinic, Istanbul/TURKEY
²M.D., Golcuk Military Hospital, Eye Clinic, Kocaeli/TURKEY
³M.D. Professor, GATA Haydarpasa Training and Research Hospital, Eye Clinic, Istanbul/TURKEY
⁴M.D. Associate Professor, GATA Haydarpasa Training and Research Hospital, Eye Clinic, Istanbul/TURKEY
⁵M.D. Asistant Professor, GATA Haydarpasa Training and Research Hospital, Eye Clinic, Istanbul/TURKEY
⁶M.D. Asistant, GATA Haydarpasa Training and Research Hospital, Infectious Diseases and Clinical Microbiology Service, Istanbul/TURKEY Endogenous fungal endophthalmitis(EFE) is a rare infection, but it maintains its importance in ophthalmology because of high potential to cause severe visual loss and also due to the limited treatment options.Candida albicans is the most common cause of EFE. Endogenous candida endophthalmitis (ECE) generally occur in patients with risk factors although we can't prove the presence of candidemia. There is an increase in the incidence of EFE by the increase of intravenous drug abuse, indwelling venous access devices, long-term antibiotic, corticosteroid or immunosuppressive drug use.For the management of treatment in ECE, we should consider that ECE develops after the candidemia due to invasive infection, and also delayed diagnosis and treatment may lead to vision loss. More importantly, we should consider that patients have a life-threatening infection. Because ECE patients have systemic medical illnesses, we should not forgotten they need a multidisciplinary management.In the presence of a simple choroiditis or mild vitritis systemic antifungal agents can be effective alone.However, in the presence of moderate-to-severe vitritis or macular involvement associated with severe vision loss, pars plana vitrectomy and/or intravitreal injection of amphotericin B has been generally preferred in addition to systemic treatment. In this report, we aim to present diagnosis and treatment management of a patient who carries many risk factors for the development of invasive candida infection and eventually developed candida endophthalmitis, and also treatment options for ECE cases in the literature. Keywords : Amphotericin B, endophthalmitis, vitrectomy