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Retina Arter Tıkanıklıkları ve Tedavisi...
Santral Retinal Ven Tıkanıklığı Güncel Tedavisi...
Central Retinal Artery Occlusion As the Cause of Unilateral Concentric Narrowing of Visual Field and Presence of Cilioretinal Artery...
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Vascular Endothelial Growth Factor and Anti VEGF Agents...
Central Retinal Artery Occlusion As the Cause of Unilateral Concentric Narrowing of Visual Field and Presence of Cilioretinal Artery...
Retina Arter Tıkanıklıkları ve Tedavisi...
Morning Glory Syndrome Associated with Retinochoroidal Coloboma...
Santral Retinal Ven Tıkanıklığı Güncel Tedavisi...
Bilateral Optic Disc Drusen
Retina-Vitreous 2019 , Vol 28 , Num 4
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Early Switch to Dexamethasone Implantation In Patients With Diabetic Macular Edema Resistant To Afl ibercept: Short-Term Results
Alper Halil BAYAT1, Burak ERDEN1, Akın ÇAKIR1, Selim BÖLÜKBAŞI1, Emine BAŞ2, Mustafa Nuri ELÇİOĞLU3
1Uz. Dr., Okmeydanı Eğitim ve Araştırma Hastanesi, Göz Kliniği, İstanbul, Türkiye
2Asist. Dr.. Okmeydanı Eğitim ve Araştırma Hastanesi, Göz Kliniği, İstanbul, Türkiye
3Prof. Dr.. Okmeydanı Eğitim ve Araştırma Hastanesi, Göz Kliniği, İstanbul, Türkiye
Purpose: To evaluate the efficacy of early switch to intravitreal dexamethasone implantation (IDI) in afl ibercept resistant diabetic macular edema (DME)

Materials and methods: In this retrospective study 21 eyes of 21 patients with persistent diabetic macular edema, who underwent a single dose IDI were examined. All of the patients had a history of at least fi ve intravitreal afl ibercept (IVA) injections. Main outcome measures were changes in best-corrected visual acuity (BCVA), central macular thickness (CMT) at 1, 2, 3 months after IDI treatment.

Results: Mean follow-up time and average number of previous IVA injections was 19.24±1.67 months and 5.35±0.6. The mean BCVA was improved from 0.73±0.57logMAR to 0.49±0.34logMAR (p=0.011), 0.34±0.29 logMAR(p=0.001), and 0.36±0.27 logMAR(p=0.001) at 1,2 and 3 months, respectively. The mean CMT was decreased from 434±90 ?m to 335±74 ?m (p<0.001), 328±46 ?m (p<0.001) and 350±85 ?m (p=0.009) at 1,2 and 3 months.Conclusion: Intravitreal dexamethasone implantation resulted in a signifi cant improvement in visual and anatomical outcomes in patients with afl ibercept resistant diabetic macular edema. Keywords : Dexamethasone, Diabetic macular edema, Optical coherence tomography

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