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¹Uz. Dr., Sağlık Bilimleri Üniversitesi Fatih Sultan Mehmet Eğitim ve Araştırma Hastanesi, Göz Hastalıkları Bölümü, İstanbul, Türkiye
²Asist. Dr., Sağlık Bilimleri Üniversitesi Fatih Sultan Mehmet Eğitim ve Araştırma Hastanesi, Göz Hastalıkları Bölümü, İstanbul, Türkiye A 54-years-old diabetic patient was referred to our clinic for fundus examination. The best corrected visual acuity(BCVA) with Snellen?s chart was 0,3; 0,5 in the right and left eye. In the fundus examination, moderate non-proliferative diabetic retinopathy(DR) signs and diabetic macular oedema(DME) were detected in both eyes. FFA was planned. The increase in macular thickness(CMT) of both eyes, DME, serous macular detachment were shown by OCT. Intravitreal anti-VEGF injections were recommended at least 3 times 1 month apart for both eyes. However, because of the patient?s diabetic foot, we were not able to treat the patient and he received a month of hyperbaric oxygen therapy(HBOT). The patient again applied, indicating that there was a rapid vision decrease in his both eyes just at the 10th day after the end of HBOT. The BCVA was 0,1; 0,05 in the right and left eye with Snellen?s chart. Increase in DME, serous macular detachment in both eyes, and optic disc neovascularization (NVD) in the left eye, was detected. This progression may be due to the patient?s poorly controlled diabetes regulation and the lack of intravitreal treatment. However, visual acuity decrease not observed during HBOT but observed just at the 10th day after the end of treatment, and the development of NVD needed questioning the situation. We think that the sudden drop in oxygen saturation after the end of HBOT may have contributed to this situation. We believe that this condition should be addressed in all patients with elevated VEGF levels, such as DR. Keywords : Hyperbaric oxygen therapy, diabetic macular edema, diabetic retinopathy